Proposal: Traditional Chinese Herbal Compounded Medicine for Antihepatoma and Liver Cancer Pain

 Because of the well-known reason, there is no miracle drug and specific medicine for the advanced liver cancer; for the advanced liver cancer patient, the target of treatment is to "improve the quality of life and extend the life"; therefore, whether the patient himself/herself or the family don't want the patient to suffer the severe pain; in the final period, the last hope for the patient and the family is that the patient lives longer without pain.  "Chen's elimination pill" is a Traditional Chinese Herbal Compounded Medicine for Antihepatoma and Liver Cancer Pain, which can help liver cancer patients.

   1.Annual production value and benefit analysis  

In recent years, the number of cancer deaths is increasing every year in China. According to newspaper the number of cancer deaths has reached 1.5 million (It is said that it is the most conservative figure and the actual number is more than 10 times), and liver cancer is the second reason for death. Although there is not accurate number of liver cancer deaths, compared to the previous figure, there are about 500,000 people in China die of liver cancer each year and the liver cancer patients that need treatments are about 1 million. As we all know, there is not efficient treatment for liver cancer right now, so what the patients and their families wish is to extend patient’s life as long as possible, especially to avoid the "horrible" pain and wish the patient could be peaceful in the final time. Right now, the drug has achieved the national anti-tumor liver cancer drug standards (certified by the Guangxi Institute of Chinese Medicine for preliminary examination: the inhibition rate, toxicity and immunity, which are passed the national requirements). The most critical point is that the medicine could cure the pain cause by liver cancer.

According to Clinical findings, when the patient takes the drug for 1-3 days, the significant efficiency for the pain is more than 50 percent and the efficiency is more than 90%.When a patient takes the medicine before the pain, the medicine not only could control or eliminate liver cancer, but also prevent the pain- about 80% of the patients will no longer have pain in their life time, which is a unique curative effect in the liver cancer medicine. Therefore, as long as there is some promotion to introduce the medicine to hospitals, even if only 10% of liver cancer patients take the medicine, and the cost is 2000 yuan (currently the cost of liver cancer of each month is more than 2000 yuan), the annual sales all over the country is 600 million yuan, If the promotion could make 20 per cent of liver cancer patients take the medicine and the annual sales of 1.2 billion yuan, which does not include any abroad sales. If the patient takes the medicine before the critical situation, the average taking time extend and there is more market potential. 

According to the current market practice, the introduction could expand the curative effect to the lung, stomach, colon cancer, nasopharyngeal carcinoma, lymphoma, prostate cancer, esophageal cancer, pancreatic cancer, renal cancer and uterine cancer…… etc. The revenue can be doubled. In fact the drugs have curative effects to a variety of cancers and the clinics also have satisfactory results, but I don’t have time to consider this topic and I support special medicine for special illness, that is, this medicine is only for liver cancer.

The medicine is made from Chinese herbal medicine using traditional technology, not containing any illegal drugs. The raw materials are available around the country. The cost is well-known by all the medicine factory.

 2. Efficacy 

The medicine easily meets national anti-tumor liver cancer drug standards, and its greatest feature is to cure the liver cancer pain. The patient no longer needs acesodyne. Generally the pain is cured  or significantly reduced in 1-3 days. The second characteristic is to prevent liver cancer pain and general pain. If the patient takes the medicine before the pain is happened, 90% of the patients will not have any pain and 80% patients will not have moderate pain. Some patients may have mild pain and only need a moderate acesodyne which is the oral analgesics and not the injections (the medicine is not valid for the pain caused by bile pain cancer).

Patients and their families all know that acesodyne (the western medicine) can only cure the pain for several hours. It is needed to be used repeatedly and has many side-effects: dry mouth, vomiting, dizziness and constipation. The side-effects also increase the pain of liver cancer patients. My medicine could prevent 80% of the liver cancer patients from the pain and the side-effects.

To cure the pain is to "improve the quality of life" of liver cancer patients. According to the large number of clinical and laboratory test results,the medicine has the same efficacy as other new medicines in killing the cancer cells. It has the ability to extend the patients’ lives. In other words,the medicine not only can improve the quality of life but also extend the patient’s life.

The development of this medicine strictly follows the Chinese medicine rules. The medicine is made by high-class Chinese herbals (the medicine is made by more than 20 kinds of animal-based drugs, the Chinese herbals are the supplements. Some “original” herbals could not be found in the pharmacy stores. The raw materials include pangolin shell, Scorpion, turtle shell and Sanqi (which is a Chinese herbal)). The medicine is selected the best primer on the drug re-processing to access rapidly to kill liver cancer cells. The medicine is developed as the anti-liver cancer drugs and its efficiency in pain-curing and the pain prevention are found completely by a large number of clinical cases. I do not deliberately pursue the target, but it is the "unintentional positive outcomes" for pain curing and prevention.

  To summary, the medicine has the following functions:

（1）Anti-liver cancer. Since the medicine is made strictly for anti-liver cancer and the raw materials are chosen for this purpose, the medicine is only for liver cancer. It only has some effects to other kinds of cancers. In other words, the medicine is best for liver cancer whether it transfers from other organs or it is primary liver cancer. The medicine can kill the liver cancer cells efficiently to eliminate, reduce and restrain the cancer.

（2）Liver cancer Pain killer. Liver cancer pain is caused by the growth of cancer tumor which stimulates or restrains the nerve. The medicine could inhibit the growth of the cancer tumor and the pain very well. So the medicine could cure the pain in different periods of the cancer. The significant efficiency is more than 50 percent and the efficiency is more than 90%, especially when it is not in the advanced period and the patient begins to take the medicine and does not stop taking it. Then, about 90% of the liver cancer patients will no longer appear life-long severe pain, far more than any of the analgesic drug. Of course, because the medicine is not pain medicine, and the drug does not include any pain killer raw material, it could not cure the pain caused by other kinds of cancers and other causes of pain.

（3）Because the medicine could anti-liver cancer, it could inhinit the liver cancer tumor. The advanced liver cancer patient taking this medicine could improve the living quality significantly and prolong life. Some patients taking the medicine have the chance to eliminate or reduce the tumor and delay the recurrence of the cancer..

 3. Development and Market Risk

 Because of the state's preferential policies on the anti-cancer drug, generally it takes 2-3 years to develop a new anti-cancer drug. The medicine was clinically proven its effectiveness by related departments according to the national standars in strict process in several years ago.The medicine is proven to satisfy the national standard. The medicine was improved twice according to the guideline of "enhance anti-cancer effect, reduce toxicity". Compared to the original one, the amended one has higher inhibition rate and lower toxicity.

 Learned from the original inspection,  five grams medicine killing the liver cancer tumor rate has reached 32.2% (at the same time, using 5 - urine fluoride of 10 mg / kg as the comparison, its inhibition rate was 37.5%. All the insiders are aware of the mysteries……),  If doubling of dose to 10 g, the inhibitory rate only increased by 1.2 per cent, or 33.4%, and the mice death rate is up to 30 percent, exceeding the national standard of 10%,  The results indicate that the toxicity of drugs are relatively large,  The increase of anti-tumor effect offset by the toxicity.  efore, as long as the original prescription was amended reduce the toxicity without reducing the existing anti-cancer effect, the medicine can significantly enhance the inhibition rate (the prescription has been amended).

Since the dose of 5 grams (drug) will be the target of anti-tumor drugs, it is known that the drug’s compounding is accurate elected, The production process can be simplified and the cost could be greatly reduced. As peers know, relatively speaking, in tje drug test in order to achieve the national standard of the inhibition rate, the doses of most of drugs are over 30 g. If it is produced to be the oral drugs, the cost will be increased.

The reason that I do not apply patent for this medicine is to secure the prescription for long term - the manufacturers should have better understanding than me. For example, the Yunnan Baiyao is unique in the battlefield , all the developed countries around the world want to figure out the prescription by their high technology. The manufacturer does not to apply patent for it and keeps the prescription confidentially until today. There are no other manufacturers can produce the medicine which has the same effect as Yunnan Baiyao. On the contrary, if Yunnan Baiyao got the patent, because of the time limit, the prescription has been shared with others long ago. This is the benefit of not to apply patent. Therefore, there is no chance to leak the prescription to others, which reduces the investment risk.

There is no medicine that not only could meet the national standard of liver cancer medicine, but also could cure and prevent the pain of liver cancer can only pain and the prevention of liver cancer, which increase the medicine’s market opportunity and lower the investment risk. In addition, this medicine has little side-effect and the raw materials are available everywhere, which does not have any resource crisis. The production process is simple and it is suitable for large and middle size pharmaceutical companies.

 So the best way is the pharmaceutical company develops the medicine by itself which has the lowest risk and investment, maximize its advantages and shorten the timeline. The R&D institute or personal investor also can apply the manufacture permit and sell the permit later to earn profit. No matter what kind of situation, the return on investment is considerable. For example, the application for the permit would cost 2,500,000 yuan, but the return would be more than 100,000,000 yuan.

  4. Transfer

  （1）Sell the prescription. To the pharmaceutical company, this is best way which is low-cost and risk and has the best benefit.

  （2）Joint development. I only provide the prescription and corresponding technology support. We share the benefit.

5. Contact Information

  Please to go this link for more information：http://www.ok289.com

  The test result of the original medicine：http://www.ok289.com/new_page_61.htm

  Email：9916@ok289.com

  Address：18 Yi Malu, Qinzhou, Guangxi, China   Zip code:535000

  Phone（fax）:0777-2813153    Cell:13977788180

  Contact：CHEN, Zhenfeng